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Thymosin Alpha-1
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⚠️ Research Use Only

These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.

What is Thymosin Alpha-1?

Thymosin Alpha-1 (Tα1) is a naturally occurring 28–amino acid peptide originally isolated from the thymus gland. It is recognized for its immunomodulatory properties, including the ability to support T-cell function, enhance innate and adaptive immunity, and regulate inflammatory pathways. Thymosin Alpha-1 continues to be studied in the context of viral infections, cancer research, and immune health.

Key Research
  • Immune system activation & T-cell support
  • Antiviral defense & infection resistance
  • Cancer immunotherapy & oncology support
  • Inflammation reduction & immune modulation
  • Vaccine adjuvant & immune priming
  • Autoimmune balance & regulation
  • Anti-aging & longevity pathways
  • Stress resilience & systemic protection
  • Liver function & detox support
  • Cardiovascular & metabolic health
Specifications
PropertyDetails
CAS Number62304-98-7
Chemical NameAc-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH (Thymosin Alpha-1); TA1; Thymalfasin
PubChem CID 16130571
Molecular FormulaC129H215N33O55
Molecular Weight≈ 3108.3 g/mol
Physical AppearanceWhite to off-white lyophilized powder
FormSynthetic thymic peptide (28 aa immunomodulator)
Container3 mL glass vial (5mg net content)
Purity ≥99% verified by HPLC & MS (batch COA via on-vial QR)
SolubilitySoluble in sterile water or compatible buffers; gentle inversion/swirl recommended. If required by your SOP, 0.22 µm filter-sterilize after reconstitution.
Intended UseLaboratory research only (RUO). Not for human or animal use.
Molecular Structure
Thymosin Alpha-1 molecular structure
FAQ

How much is in each vial?

Each vial contains precisely the amount indicated on the label. For instance, a 10mg vial includes precisely 10mg of lyophilized peptide. Researchers may divide it into smaller fractions, such as four 2.5mg portions, while the total amount remains 10mg.

Does it come with instructions?

USA Peptides Direct products are designated for in vitro research. Prior to working with them, conduct thorough research. Our team will offer general assistance via text post-purchase.

What other supplies are needed?

Peptides come as lyophilized powder. They are not reconstituted, and any necessary bacteriostatic water or syringes must be obtained separately for research purposes.

How long does a vial last?

Peptides remain stable for up to 2 years in lyophilized powder form. After reconstitution, refrigerate and expect stability for about 2 months.

What in-vitro assays is Thymosin Alpha-1 commonly used in?

Typical RUO applications include innate-immune pathway reporters, dendritic-cell maturation panels, T-cell co-culture models, and LC–MS/MS method development.
References
  1. Goldstein, A. L., et al. “Thymosin alpha 1: Biological activities, applications and potential therapeutic benefits.” Annals of the New York Academy of Sciences 685, 1993, 179–189. [Link]
  2. Romani, L., et al. “Thymosin alpha 1: Mechanisms of action and therapeutic potential.” Expert Opinion on Biological Therapy 10(5), 2010, 787–791. [Link]
  3. Garaci, E. “Thymosin alpha 1: Reflections on three decades of research.” Annals of the New York Academy of Sciences 1194, 2010, 14–20. [Link]
  4. Wang, F. S., et al. “Thymosin alpha-1 therapy in chronic hepatitis B: A randomized controlled trial.” Hepatology 27(6), 1998, 1383–1387. [Link]
  5. Costantini, C., et al. “Thymosin alpha-1 in infectious diseases and cancer: the yin and yang of immune homeostasis.” Expert Opinion on Biological Therapy 9(7), 2009, 875–885. [Link]
Thymosin Alpha-1
Thymosin Alpha-1
5mg
$59.00
One-time

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Quality, Storage & Handling

Each lot is confirmed by HPLC (purity) and MS (identity); QR on the vial links to the batch COA. Independent U.S. labs verify purityquantity, and endotoxin.

  • Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
  • After reconstitution: Use neutral, oxygen-poor buffer when possible; aliquot and store at ≤−20 °C; avoid repeated freeze–thaw.
  • Working solutions: Prepare fresh; minimize exposure to light/alkaline pH to reduce degradation.

Shipping

Ships in validated cold-chain packaging. In-stock orders placed before the daily cutoff dispatch the same day2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included.

Compliance & Research Use Only Disclaimer

For laboratory research only. All articles are product information provided on this website are for informational and educational purposes only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available via QR or upon request.