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Tesamorelin
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⚠️ Research Use Only

These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.

What is Tesamorelin?

Tesamorelin is a synthetic analogue of growth hormone–releasing hormone (GHRH), consisting of 44 amino acids with a trans-3-hexenoyl group at the N-terminus to enhance stability. It stimulates the pituitary to release endogenous growth hormone, which increases IGF-1 and supports fat metabolism, body composition, and cellular repair. Tesamorelin is FDA-approved for the treatment of HIV-associated lipodystrophy and is being studied for additional metabolic and anti-aging applications.

Key Research
  • Growth hormone release & IGF-1 stimulation
  • Reduction of visceral adipose tissue (VAT)
  • Body composition & fat metabolism
  • Muscle growth & performance support
  • Bone health & density
  • Cardiovascular & metabolic health
  • Cognitive support & neuroprotection
  • Anti-aging & longevity pathways
  • Sleep quality & circadian rhythm
  • Stress resilience & systemic protection
Specifications
PropertyDetails
CAS Number218949-48-5
Chemical NameSynthetic GHRH analog, 44 amino acids with N-terminal modification
PubChem CID 16137828
Molecular FormulaC221H366N72O67S
Molecular Weight≈ 5135.9 g/mol
Physical AppearanceWhite to off-white lyophilized powder
FormSynthetic GHRH analogue (44 aa polypeptide, N-terminal stabilized)
Container3 mL glass vial (5 mg net content)
Purity≥99% verified by HPLC & MS (batch COA via on-vial QR)
SolubilitySoluble in sterile water or compatible buffer; gently invert until dissolved; filter-sterilize if needed
Intended UseLaboratory research only (RUO). Not for human or animal use.
Molecular Structure
Tesamorelin molecular structure
FAQ

How much is in each vial?

Each vial contains precisely the amount indicated on the label. For instance, a 10mg vial includes precisely 10mg of lyophilized peptide. Researchers may divide it into smaller fractions, such as four 2.5mg portions, while the total amount remains 10mg.

Does it come with instructions?

USA Peptides Direct products are designated for in vitro research. Prior to working with them, conduct thorough research. Our team will offer general assistance via text post-purchase.

What other supplies are needed?

Peptides come as lyophilized powder. They are not reconstituted, and any necessary bacteriostatic water or syringes must be obtained separately for research purposes.

How long does a vial last?

Peptides remain stable for up to 2 years in lyophilized powder form. After reconstitution, refrigerate and expect stability for about 2 months.

Which in-vitro or experimental assays is Tesamorelin commonly used in?

Research applications include studies of growth hormone release, metabolic regulation, fat redistribution, and body composition models.
References
  1. Falutz, J., et al. “Metabolic effects of a growth hormone–releasing factor in patients with HIV.” New England Journal of Medicine 357(23), 2007, 2359–2370. [Link]
  2. Falutz, J., et al. “Long-term safety and effects of tesamorelin, a growth hormone–releasing factor analogue, in HIV patients with abdominal fat accumulation.” AIDS 22(14), 2008, 1719–1728. [Link]
  3. Allas, S., et al. “Safety and efficacy of tesamorelin, a growth hormone–releasing factor analogue, in HIV-infected patients with abdominal fat accumulation: pooled analysis of two multicenter trials.” Journal of Clinical Endocrinology & Metabolism 97(9), 2012, 3493–3502. [Link]
  4. Guaraldi, G., et al. “Efficacy and safety of tesamorelin in the treatment of abdominal fat accumulation in HIV-infected patients.” Current HIV Research 11(6), 2013, 537–549. [Link]
  5. Erlandson, K. M., et al. “Effects of tesamorelin on liver fat and visceral adipose tissue in HIV-infected adults with nonalcoholic fatty liver disease.” Journal of Clinical Endocrinology & Metabolism 104(12), 2019, 5641–5653. [Link]
Tesamorelin
Tesamorelin
5mg
$69.00
One-time

Why Buy from USA Peptides Direct

  • USA Made
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Quality, Storage & Handling

Each lot is confirmed by HPLC (purity) and MS (identity); QR on the vial links to the batch COA. Independent U.S. labs verify purityquantity, and endotoxin.

  • Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
  • After reconstitution: Use neutral, oxygen-poor buffer when possible; aliquot and store at ≤−20 °C; avoid repeated freeze–thaw.
  • Working solutions: Prepare fresh; minimize exposure to light/alkaline pH to reduce degradation.

Shipping

Ships in validated cold-chain packaging. In-stock orders placed before the daily cutoff dispatch the same day2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included.

Compliance & Research Use Only Disclaimer

For laboratory research only. All articles are product information provided on this website are for informational and educational purposes only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available via QR or upon request.