NAD+
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$69.00
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⚠️ Research Use Only
These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.
What is NAD+?
Key Research
Certificate of Analysis
Third-party tested for 99% purity — click to view lab results.
Specifications
| Property | Details |
|---|---|
| CAS Number | 53-84-9 |
| Chemical Name | β-Nicotinamide adenine dinucleotide (oxidized form);NAD+; Nadide |
| PubChem CID | 5892 |
| Molecular Formula | C21H27N7O14P2 |
| Molecular Weight | ≈ 663.43 g/mol |
| Physical Appearance | White to off-white lyophilized powder |
| Form | Oxidized dinucleotide cofactor (anhydrous) |
| Container | Glass vial (500 / 1000 mg net content) |
| Purity | ≥99% verified by HPLC & MS (batch COA via on-vial QR) |
| Solubility | Readily soluble in sterile water and compatible neutral buffers; prepare fresh; protect from light; avoid high pH/alkaline conditions |
| Intended Use | Laboratory research only (RUO). Not for human or animal use. |
Molecular Structure
FAQ
How much is in each vial?
Each vial contains precisely the amount indicated on the label. For instance, a 10mg vial includes precisely 10mg of lyophilized peptide. Researchers may divide it into smaller fractions, such as four 2.5mg portions, while the total amount remains 10mg.
Does it come with instructions?
USA Peptides Direct products are designated for in vitro research. Prior to working with them, conduct thorough research. Our team will offer general assistance via text post-purchase.
What other supplies are needed?
Peptides come as lyophilized powder. They are not reconstituted, and any necessary bacteriostatic water or syringes must be obtained separately for research purposes.
How long does a vial last?
Peptides remain stable for up to 2 years in lyophilized powder form. After reconstitution, refrigerate and expect stability for about 2 months.
Is this the oxidized form?
Yes. This product is NAD+(oxidized). For reduced NADH or NADP(H), see our catalog.
What purity is provided?
Each vial is ≥99% by HPLC with MS identity confirmation; third-party testing is performed on every lot (COA via QR).
How should I reconstitute it?
Use sterile water or a neutral, compatible buffer; gently invert to dissolve. Prepare fresh working solutions, aliquot, and avoid alkaline pH and repeated freeze–thaw.
Which in-vitro assays is NAD+ commonly used in?
Typical RUO uses include dehydrogenase kinetics (340 nm), sirtuin and PARP assays, NAD+-dependent ligase reactions, and LC–MS method development for dinucleotides.
References
- Neelakantan H, Brightwell CR, Graber TG, Maroto R, Wang HL, McHardy SF, Papaconstantinou J, Fry CS, Watowich SJ. Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle. Biochem Pharmacol. 2019 May;163:481-492. doi: 10.1016/j.bcp.2019.02.008. Epub 2019 Feb 10. PMID: 30753815; PMCID: PMC6469996. [Link]
- Mendelsohn AR, Larrick JW. Partial reversal of skeletal muscle aging by restoration of normal NAD⁺ levels. Rejuvenation Res. 2014 Feb;17(1):62-9. doi: 10.1089/rej.2014.1546. PMID: 24410488. [Link]
- Shan C, Gong YL, Zhuang QQ, Hou YF, Wang SM, Zhu Q, Huang GR, Tao B, Sun LH, Zhao HY, Li ST, Liu JM. Protective effects of β- nicotinamide adenine dinucleotide against motor deficits and dopaminergic neuronal damage in a mouse model of Parkinson's disease. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Aug 30;94:109670. doi: 10.1016/j.pnpbp.2019.109670. Epub 2019 Jun 17. PMID: 31220519. [Link]
- Lloret A, Beal MF. PGC-1α, Sirtuins and PARPs in Huntington's Disease and Other Neurodegenerative Conditions: NAD+ to Rule Them All. Neurochem Res. 2019 Oct;44(10):2423-2434. doi: 10.1007/s11064-019-02809-1. Epub 2019 May 7. PMID: 31065944. [Link]
NAD+
500mg
$69.00
One-time
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Quality, Storage & Handling
Each lot is confirmed by HPLC (purity) and MS (identity); QR on the vial links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
- After reconstitution: Use neutral, oxygen-poor buffer when possible; aliquot and store at ≤−20 °C; avoid repeated freeze–thaw.
- Working solutions: Prepare fresh; minimize exposure to light/alkaline pH to reduce degradation.
Shipping
Ships in validated cold-chain packaging. In-stock orders placed before the daily cutoff dispatch the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included.
Compliance & Research Use Only Disclaimer
For laboratory research only. All articles are product information provided on this website are for informational and educational purposes only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available via QR or upon request.