GLP-3
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$99.00
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⚠️ Research Use Only
These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.
What is GLP-3?
Key Research
Specifications
| Property | Details |
|---|---|
| CAS Number | Not assigned for this research analog; see lot COA |
| PubChem CID | Not assigned for this research analog; see lot COA |
| Molecular Formula | Sequence- and salt-dependent (reported on COA) |
| Molecular Weight | Sequence- and salt-dependent (reported on COA) |
| Physical Appearance | White to off-white lyophilized powder |
| Form | Synthetic peptide (triple agonist) |
| Container | 3 mL glass vial (10 mg net content) |
| Purity | ≥99% by HPLC; identity by MS (batch COA via on-vial QR) |
| Solubility | Soluble in sterile water or neutral aqueous buffers; gentle inversion/brief sonication may aid dissolution. If required by your SOP, 0.22 µm filter after reconstitution. |
| Intended Use | Laboratory research only (RUO). Not for human or animal use. |
FAQ
How much is in each vial?
Each vial contains precisely the amount indicated on the label. For instance, a 10mg vial includes precisely 10mg of lyophilized peptide. Researchers may divide it into smaller fractions, such as four 2.5mg portions, while the total amount remains 10mg.
Does it come with instructions?
USA Peptides Direct products are designated for in vitro research. Prior to working with them, conduct thorough research. Our team will offer general assistance via text post-purchase.
What other supplies are needed?
Peptides come as lyophilized powder. They are not reconstituted, and any necessary bacteriostatic water or syringes must be obtained separately for research purposes.
How long does a vial last?
Peptides remain stable for up to 2 years in lyophilized powder form. After reconstitution, refrigerate and expect stability for about 2 months.
Is this the same as clinical retatrutide?
No. This is a research-only analog configured for in-vitro work. It is not intended for human or animal use.
Can you share the exact sequence?
The lot-specific primary sequence, any side-chain/lipidation details, and calculated formula/MW are disclosed on the COA linked by the on-vial QR.
Which in-vitro assays is this commonly used in?
Typical RUO applications include GLP-1R/GIPR/GCGR cAMP assays, β-arrestin/internalization workflows, radioligand binding, and LC–MS method development.
References
- Coskun, T., et al. “LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist, robustly reduces body weight via enhanced energy expenditure in preclinical models.” Cell Metabolism 34(10), 2022, 1486–1501.e7 [Link]
- Frias, J. P., et al. “LY3437943, a triple glucagon, GIP, and GLP-1 receptor agonist, in people with type 2 diabetes: a randomised, placebo-controlled, multiple ascending dose phase 1b trial.” The Lancet Diabetes & Endocrinology 10(12), 2022, 873–884. [Link]
- Jastreboff, A. M., et al. “Triple–Hormone–Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial.” New England Journal of Medicine 389(2), 2023, 132–144. [Link]
- Wu, X., et al. “Structural insights into the triple agonism at GLP-1R, GIPR and GCGR by the dual-incretin agonist LY3437943 (Retatrutide).” Nature Structural & Molecular Biology 31(8), 2024, 702–712 [Link]
- Neuser, D., et al. “Inotropic effects of the triple agonist retatrutide (LY3437943) in isolated human atrial preparations.” Frontiers in Pharmacology 16, 2024, Article 1403874. [Link]
GLP-3
5mg
$99.00
One-time
Why Buy from USA Peptides Direct
- USA Made
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- GMP-Standard lyophilization, documented & traceable
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Quality, Storage & Handling
Each lot is confirmed by HPLC (purity) and MS (identity); QR on the vial links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
- After reconstitution: Use neutral, oxygen-poor buffer when possible; aliquot and store at ≤−20 °C; avoid repeated freeze–thaw.
- Working solutions: Prepare fresh; minimize exposure to light/alkaline pH to reduce degradation.
Shipping
Ships in validated cold-chain packaging. In-stock orders placed before the daily cutoff dispatch the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included.
Compliance & Research Use Only Disclaimer
For laboratory research only. All articles are product information provided on this website are for informational and educational purposes only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available via QR or upon request.