LL-37
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$39.95
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⚠️ Research Use Only
These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.
What is LL-37?
Key Research
Specifications
| Property | Details |
|---|---|
| CAS Number | 154947-66-7 |
| Chemical Name | Human cathelicidin LL-37 (C-terminal fragment of hCAP18) |
| PubChem CID | 16198951 |
| Molecular Formula | C205H340N60O53 (free base) |
| Molecular Weight | ≈ 4493.3 g/mol (free base) |
| Physical Appearance | White to off-white lyophilized powder |
| Form | Synthetic antimicrobial and immunomodulatory peptide (lyophilized acetate salt) |
| Container | 3 mL Type I glass vial; butyl stopper; flip-off seal |
| Purity | ≥99% by HPLC; identity by MS (batch COA via on-vial QR) |
| Solubility | Soluble in sterile water or neutral buffers; for higher concentrations, pre-wet with ≤0.1% acetic acid, then bring to final buffer. If sterility is required by your SOP, 0.22 µm filter after dissolution |
| Intended Use | Laboratory research only (RUO). Not for human or animal use. |
Molecular Structure
FAQ
How much is in each vial?
Each vial contains precisely the amount indicated on the label. For instance, a 10mg vial includes precisely 10mg of lyophilized peptide. Researchers may divide it into smaller fractions, such as four 2.5mg portions, while the total amount remains 10mg.
Does it come with instructions?
USA Peptides Direct products are designated for in vitro research. Prior to working with them, conduct thorough research. Our team will offer general assistance via text post-purchase.
What other supplies are needed?
Peptides come as lyophilized powder. They are not reconstituted, and any necessary bacteriostatic water or syringes must be obtained separately for research purposes.
How long does a vial last?
Peptides remain stable for up to 2 years in lyophilized powder form. After reconstitution, refrigerate and expect stability for about 2 months.
Is LL-37 the only human cathelicidin?
Yes, the CAMP gene encodes the precursor (hCAP18) from which the active 37-mer LL-37 is generated; LL-37 is the sole human cathelicidin.
What purity do you provide?
Each 10 mg vial is ≥99% by HPLC with MS identity confirmation; third-party testing is performed on every lot (COA via on-vial QR).
Do you provide a PubChem image?
Yes, the 2D structure above is rendered from PubChem CID 16198951 for LL-37. (Identifier also listed by multiple reagent databases.)
How should I reconstitute it?
Dissolve in sterile water or a compatible buffer; gently invert until fully dissolved. If your SOP requires sterility, 0.22 µm filter and aliquot to avoid repeat freeze–thaw.
References
- Dürr, U. H. N., et al. The human cathelicidin LL-37, a multifunctional peptide of the innate immune system. Biochimica et Biophysica Acta 1758(9), 2006, 1408–1425. [Link]
- Koczulla, R., et al. An angiogenic role for the human peptide antibiotic LL-37/hCAP-18. Proceedings of the National Academy of Sciences (PNAS) 100(9), 2003, 6125–6130. [Link]
- Zaiou, M., et al. Regulation of innate defense mechanisms by cathelicidin antimicrobial peptides. Immunologic Research 35(2), 2006, 195–215. [Link]
LL-37
5mg
$39.95
One-time
Why Buy from USA Peptides Direct
- USA Made
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- GMP-Standard lyophilization, documented & traceable
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- Batch Tracking with QR Code Verification
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Quality, Storage & Handling
Each lot is confirmed by HPLC (purity) and MS (identity); QR on the vial links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
- After reconstitution: Use neutral, oxygen-poor buffer when possible; aliquot and store at ≤−20 °C; avoid repeated freeze–thaw.
- Working solutions: Prepare fresh; minimize exposure to light/alkaline pH to reduce degradation.
Shipping
Ships in validated cold-chain packaging. In-stock orders placed before the daily cutoff dispatch the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included.
Compliance & Research Use Only Disclaimer
For laboratory research only. All articles are product information provided on this website are for informational and educational purposes only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available via QR or upon request.