Kisspeptin-10
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$29.95
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⚠️ Research Use Only
These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.
What is Kisspeptin-10?
Key Research
Specifications
| Property | Details |
|---|---|
| CAS Number | 374675-21-5 |
| Chemical Name | Kisspeptin-10 (human), Metastin 45–54 |
| PubChem CID | 25240297 |
| Molecular Formula | C63H83N17O14 |
| Molecular Weight | ≈ 1302.45 g/mol |
| Physical Appearance | White to off-white lyophilized powder |
| Form | Synthetic neuropeptide analog (lyophilized acetate salt) |
| Container | 3 mL Type I glass vial (5 mg net content) |
| Purity | ≥ 99% (verified by HPLC & MS; 3rd-party tested) |
| Solubility | Soluble in sterile water or compatible buffer; if needed, pre-wet with ≤0.1% acetic acid or minimal DMSO, then bring to final buffer. 0.22 µm filter-sterilize if required. |
| Intended Use | Laboratory research only (RUO). Not for human or animal use. |
Molecular Structure
FAQ
How much is in each vial?
Each vial contains precisely the amount indicated on the label. For instance, a 10mg vial includes precisely 10mg of lyophilized peptide. Researchers may divide it into smaller fractions, such as four 2.5mg portions, while the total amount remains 10mg.
Does it come with instructions?
USA Peptides Direct products are designated for in vitro research. Prior to working with them, conduct thorough research. Our team will offer general assistance via text post-purchase.
What other supplies are needed?
Peptides come as lyophilized powder. They are not reconstituted, and any necessary bacteriostatic water or syringes must be obtained separately for research purposes.
How long does a vial last?
Peptides remain stable for up to 2 years in lyophilized powder form. After reconstitution, refrigerate and expect stability for about 2 months.
What is the primary function of Kisspeptin-10?
Kisspeptin-10 activates KISS1 receptors (GPR54) in the hypothalamus, triggering the release of GnRH, which in turn stimulates LH and FSH secretion — essential for reproductive hormone balance and gonadal function.
What purity is provided?
Each vial is ≥99% purity, verified by HPLC and mass spectrometry, with full COA and MS identity confirmation available via QR code.
How should I reconstitute it?
Use sterile bacteriostatic or distilled water. Gently invert until fully dissolved; avoid shaking. Store reconstituted peptide at 2–8 °C and use within 7–10 days.
What are the research applications of Kisspeptin-10?
Studies focus on its role in fertility regulation, pubertal development, hormone secretion, and neuroendocrine signaling. Additional research explores its influence on metabolism, stress response, and emotional well-being.
How does Kisspeptin-10 differ from full-length Kisspeptin?
Kisspeptin-10 represents the biologically active fragment of the native peptide and is more stable in research settings, with comparable receptor binding and potency.
References
- Han, S.-K., et al. “Activation of Gonadotropin-Releasing Hormone Neurons by Kisspeptin as a Neuroendocrine Switch for the Onset of Puberty.” Journal of Neuroscience, 2005. PMID: 16339030 [Link]
- Zhang, C., et al. “Kisspeptin Depolarizes Gonadotropin-Releasing Hormone Neurons through Activation of TRPC-Like Cationic Channels.” Journal of Neuroscience, 2008. PMID: 18434521 [Link]
- Liu, X., Lee, K., Herbison, A. E. “Kisspeptin Excites Gonadotropin-Releasing Hormone Neurons through a Phospholipase C/Calcium-Dependent Pathway Regulating Multiple Ion Channels.” Endocrinology, 2008. PMID: 18483150 [Link]
- Pielecka-Fortuna, J., Moenter, S. M. “Kisspeptin Increases γ-Aminobutyric Acidergic and Glutamatergic Transmission Directly to GnRH Neurons in an Estradiol-Dependent Manner.” Endocrinology, 2010. PMID: 19880809 [Link]
Kisspeptin-10
5mg
$29.95
One-time
Why Buy from USA Peptides Direct
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Quality, Storage & Handling
Each lot is confirmed by HPLC (purity) and MS (identity); QR on the vial links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
- After reconstitution: Use neutral, oxygen-poor buffer when possible; aliquot and store at ≤−20 °C; avoid repeated freeze–thaw.
- Working solutions: Prepare fresh; minimize exposure to light/alkaline pH to reduce degradation.
Shipping
Ships in validated cold-chain packaging. In-stock orders placed before the daily cutoff dispatch the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included.
Compliance & Research Use Only Disclaimer
For laboratory research only. All articles are product information provided on this website are for informational and educational purposes only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available via QR or upon request.