IGF-1 LR3
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$79.95
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⚠️ Research Use Only
These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.
What is IGF-1 LR3?
Key Research
Specifications
| Property | Details |
|---|---|
| CAS Number | 946870-92-4 |
| Chemical Name | Insulin-Like Growth Factor-1, Long R3 (IGF-1 LR3) |
| PubChem CID | N/A (no dedicated LR3 entry) |
| Molecular Formula | C400H625N111O115S9 |
| Molecular Weight | ~9.1 kDa |
| Physical Appearance | White to off-white lyophilized powder |
| Form | Recombinant human insulin-like growth factor analog (lyophilized peptide base) |
| Container | 3 mL Type I glass vial (1 mg net content) |
| Purity | ≥ 99% (verified by HPLC & MS; third-party tested) |
| Solubility | Soluble in sterile water; for concentrated stocks, pre-wet with 10 mM HCl or ≤0.1% acetic acid, then dilute into final buffer. 0.22 µm filter-sterilize if required. |
| Intended Use | Laboratory research only (RUO). Not for human or animal use. |
FAQ
How much is in each vial?
Each vial contains precisely the amount indicated on the label. For instance, a 10mg vial includes precisely 10mg of lyophilized peptide. Researchers may divide it into smaller fractions, such as four 2.5mg portions, while the total amount remains 10mg.
Does it come with instructions?
USA Peptides Direct products are designated for in vitro research. Prior to working with them, conduct thorough research. Our team will offer general assistance via text post-purchase.
What other supplies are needed?
Peptides come as lyophilized powder. They are not reconstituted, and any necessary bacteriostatic water or syringes must be obtained separately for research purposes.
How long does a vial last?
Peptides remain stable for up to 2 years in lyophilized powder form. After reconstitution, refrigerate and expect stability for about 2 months.
What does “LR3” mean?
“Long Arg3” refers to the modified structure of IGF-1 LR3 — a 13-amino-acid extension and arginine substitution at position 3 — that reduces IGF-binding protein interaction, increasing its activity and half-life.
What purity is provided?
Each vial is ≥99% purity, confirmed by HPLC and mass spectrometry, with COA and MS identity verification included for every lot.
How should I reconstitute it?
Reconstitute with sterile water for injection (WFI) or bacteriostatic water. Gently invert to dissolve; do not shake. Store at 2–8 °C and use within 7–10 days.
What is IGF-1 LR3 studied for?
It is widely studied for its potential to enhance muscle cell growth, accelerate recovery, improve glucose metabolism, and support tissue regeneration in models of aging and metabolic optimization.
How does IGF-1 LR3 differ from native IGF-1?
The LR3 variant binds less tightly to carrier proteins, extending its half-life from minutes to over 20 hours, resulting in prolonged activity and enhanced cellular uptake in research applications.
References
- Boomsma, J., et al. “Three-dimensional structure of human insulin-like growth factor I/II.” Biochemistry, 2002. [Link]
- Pfeffer, L. A., et al. “The insulin-like growth factor (IGF)-I E-peptides modulate cell entry of the mature IGF-I protein.” Mol Biol Cell, 2009. [Link]
- Chamoun, D., et al. “Regulation of granulosa cell-derived IGF-binding proteins (IGFBP-4 and IGFBP-5).” Biol Reprod, 2002. [Link]
IGF-1 LR3
1mg
$79.95
One-time
Why Buy from USA Peptides Direct
- USA Made
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- GMP-Standard lyophilization, documented & traceable
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Quality, Storage & Handling
Each lot is confirmed by HPLC (purity) and MS (identity); QR on the vial links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
- After reconstitution: Use neutral, oxygen-poor buffer when possible; aliquot and store at ≤−20 °C; avoid repeated freeze–thaw.
- Working solutions: Prepare fresh; minimize exposure to light/alkaline pH to reduce degradation.
Shipping
Ships in validated cold-chain packaging. In-stock orders placed before the daily cutoff dispatch the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included.
Compliance & Research Use Only Disclaimer
For laboratory research only. All articles are product information provided on this website are for informational and educational purposes only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available via QR or upon request.