Epitalon
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$29.95
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⚠️ Research Use Only
These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.
What is Epitalon?
Key Research
Specifications
| Property | Details |
|---|---|
| CAS Number | 307297-39-8 |
| Chemical Name | H-Ala-Glu-Asp-Gly-OH (Epitalon / Epithalon / AEDG) |
| PubChem CID | 219042 |
| Molecular Formula | C14H22N4O9 |
| Molecular Weight | ≈ 390.35 g/mol |
| Physical Appearance | White to off-white lyophilized powder |
| Form | Synthetic tetrapeptide (lyophilized acetate salt) |
| Container | 3 mL glass vial (10 mg net content) |
| Purity | ≥ 99% verified by HPLC & MS |
| Solubility | Soluble in sterile water or compatible aqueous buffer; gently invert until dissolved; filter-sterilize (0.22 µm) if required by your method |
| Intended Use | Laboratory research only (RUO). Not for human or animal use. |
Molecular Structure
FAQ
How much is in each vial?
Each vial contains precisely the amount indicated on the label. For instance, a 10mg vial includes precisely 10mg of lyophilized peptide. Researchers may divide it into smaller fractions, such as four 2.5mg portions, while the total amount remains 10mg.
Does it come with instructions?
USA Peptides Direct products are designated for in vitro research. Prior to working with them, conduct thorough research. Our team will offer general assistance via text post-purchase.
What other supplies are needed?
Peptides come as lyophilized powder. They are not reconstituted, and any necessary bacteriostatic water or syringes must be obtained separately for research purposes.
How long does a vial last?
Peptides remain stable for up to 2 years in lyophilized powder form. After reconstitution, refrigerate and expect stability for about 2 months.
Is Epitalon naturally occurring?
Epitalon is the synthetic version of Epithalamin, a peptide complex first isolated from bovine pineal tissue. The synthetic form is identical in amino acid sequence and structure, allowing for standardized purity and research reproducibility.
How should I reconstitute it?
Use sterile water for injection (WFI) or a neutral buffer. Gently invert to dissolve. Do not shake vigorously. Store reconstituted peptide refrigerated (2–8 °C) and use within 7–10 days.
Which pathways are influenced by Epitalon?
Epitalon has been shown to modulate telomerase (hTERT) expression, pineal melatonin secretion, and p53/p21 cellular senescence regulators, aligning it closely with studies in anti-aging and genomic protection.
References
- Khavinson, V. Kh., I. E. Bondarev, and A. A. Butyugov. “Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells.” Bulletin of Experimental Biology and Medicine, vol. 135, no. 6, 2003, pp. 590–592. [Link]
- Khavinson, V., et al. “Peptide Epitalon Activates Chromatin at the Old Age.” Neuro Endocrinology Letters, vol. 24, no. 5, 2003, pp. 329–333. [Link]
- Lin’kova, N. S., et al. “Peptide Regulation of Skin Fibroblast Functions during Their Aging In Vitro.” Bulletin of Experimental Biology and Medicine, vol. 161, no. 1, 2016, pp. 175–178. [Link]
- Wałajtys-Rode, E., et al. “Overview of Epitalon—Highly Bioactive Pineal Tetrapeptide with Multiple Biological Effects.” International Journal of Molecular Sciences, vol. 26, no. 6, 2025, 2691. [Link]
Epitalon
10mg
$29.95
One-time
Why Buy from USA Peptides Direct
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Quality, Storage & Handling
Each lot is confirmed by HPLC (purity) and MS (identity); QR on the vial links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
- After reconstitution: Use neutral, oxygen-poor buffer when possible; aliquot and store at ≤−20 °C; avoid repeated freeze–thaw.
- Working solutions: Prepare fresh; minimize exposure to light/alkaline pH to reduce degradation.
Shipping
Ships in validated cold-chain packaging. In-stock orders placed before the daily cutoff dispatch the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included.
Compliance & Research Use Only Disclaimer
For laboratory research only. All articles are product information provided on this website are for informational and educational purposes only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available via QR or upon request.