DSIP
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$20.00
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⚠️ Research Use Only
These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.
What is DSIP?
Key Research
Specifications
| Property | Details |
|---|---|
| CAS Number | 62568-57-4 |
| Chemical Name | Delta Sleep-Inducing Peptide (DSIP); synonym: Emideltide |
| PubChem CID | Base peptide: 68816 | Phosphate: 172600 |
| Molecular Formula | C35H48N10O15 |
| Molecular Weight | Base: ~848.8 g/mol | Phosphate salt: ~928.8 g/mol |
| Physical Appearance | White to off-white lyophilized powder |
| Form | Endogenous neuropeptide (nonapeptide, 9 aa) |
| Container | 3 mL glass vial (2 mg net content) |
| Purity | ≥99% verified by HPLC & MS (batch COA via on-vial QR) |
| Solubility | Soluble in sterile water or compatible aqueous buffer (e.g., PBS). Gently mix until fully dissolved; filter-sterilize (0.22 µm) if required. |
| Intended Use | Laboratory research only (RUO). Not for human or animal use. |
Molecular Structure
FAQ
How much is in each vial?
Each vial contains precisely the amount indicated on the label. For instance, a 10mg vial includes precisely 10mg of lyophilized peptide. Researchers may divide it into smaller fractions, such as four 2.5mg portions, while the total amount remains 10mg.
Does it come with instructions?
USA Peptides Direct products are designated for in vitro research. Prior to working with them, conduct thorough research. Our team will offer general assistance via text post-purchase.
What other supplies are needed?
Peptides come as lyophilized powder. They are not reconstituted, and any necessary bacteriostatic water or syringes must be obtained separately for research purposes.
How long does a vial last?
Peptides remain stable for up to 2 years in lyophilized powder form. After reconstitution, refrigerate and expect stability for about 2 months.
Is this the natural sleep peptide?
Yes. DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide first identified in the hypothalamus and associated with sleep regulation.
Which in-vitro or experimental assays is DSIP commonly used in?
Typical RUO applications include sleep physiology research, stress and endocrine modulation studies, neuroprotection assays, and circadian rhythm models.
What is its stability?
Lyophilized powder is stable at –20 °C; reconstituted solutions should be stored at 2–8 °C and used within a short timeframe.
References
- Nakamura, A., et al. “Delta-sleep-inducing peptide (DSIP) stimulates the release of immunoreactive Met-enkephalin from rat lower brainstem slices in vitro.” Brain Research, 1989. [Link]
- Nakamura, A., K. Sakai, Y. Takahashi, and H. Shiomi. “Characterization of DSIP-evoked release of Met-enkephalin from brain synaptosomes in rats.” Journal of Neurochemistry, 57(3), 1991, pp. 1013–1018. [Link]
- Graf, M. V., and G. A. Schoenenberger. “Delta Sleep-Inducing Peptide modulates the stimulation of rat pineal N-acetyltransferase activity by an α1-adrenergic receptor mechanism.” Journal of Neurochemistry, 48(4), 1987, pp. 1252–1257. [Link]
- Sudakova, K. V., P. E. Umriukhina, and K. S. Rayevsky. “Delta-sleep-inducing peptide and neuronal activity after glutamate microiontophoresis: the role of NMDA-receptors.” Pathophysiology, 11(2), 2004, pp. 81–86. [Link]
- Augustijns, P., and R. T. Borchardt. “Transport and metabolism of delta-sleep-inducing peptide in cultured human intestinal epithelial (Caco-2) cell monolayers.” Drug Metabolism and Disposition, 1996. [Link]
DSIP
2mg
$20.00
One-time
Why Buy from USA Peptides Direct
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Quality, Storage & Handling
Each lot is confirmed by HPLC (purity) and MS (identity); QR on the vial links to the batch COA. Independent U.S. labs verify purity, quantity, and endotoxin.
- Storage (lyophilized): −20 °C long-term or 2–8 °C short-term; keep desiccated and protected from light.
- After reconstitution: Use neutral, oxygen-poor buffer when possible; aliquot and store at ≤−20 °C; avoid repeated freeze–thaw.
- Working solutions: Prepare fresh; minimize exposure to light/alkaline pH to reduce degradation.
Shipping
Ships in validated cold-chain packaging. In-stock orders placed before the daily cutoff dispatch the same day. 2-Day FedEx/UPS is standard, with overnight options available. Automated text/email updates included.
Compliance & Research Use Only Disclaimer
For laboratory research only. All articles are product information provided on this website are for informational and educational purposes only. Not a drug, cosmetic, food, or household chemical. Not for human or animal use, diagnostic, or therapeutic applications. Buyers warrant they are qualified to handle RUO materials under applicable laws and institutional guidelines. COAs available via QR or upon request.